Crystallization (Comment) | Organism |
---|---|
sitting drop vapor diffusion method, using 0.01 M nickel chloride, 0.1M Tris (pH 8.5), 1.0 M lithium sulfate | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P54802 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
glycoprotein | the enzyme has 6 putative N-glycosylation sites at N261, N272, N435, N503, N526 and N532 | Homo sapiens |
Purification (Comment) | Organism |
---|---|
butyl-Sepharose 4 column chromatography and Q-Sepharose column chromatography | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HT-1080 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-methylumbelliferyl N-acetyl-alpha-D-glucosaminide + H2O | - |
Homo sapiens | 4-methylumbelliferone + N-acetyl-alpha-D-glucosamine | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotrimer | x-ray crystallography | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
alpha-acetylglucosaminidase | - |
Homo sapiens |
NAG | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
malfunction | alpha-N-acetylglucosaminidase is a key enzyme in the pathogenesis of Sanfilippo syndrome B | Homo sapiens |